Response: Dapsone advantages over trimethoprim-sulfamethoxazole for Pneumocystis pneumonia prophylaxis in immunobullous patients

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Limited effect of trimethoprim-sulfamethoxazole prophylaxis on Pneumocystis carinii.

Trimethoprim-sulfamethoxazole has been proven effective in the treatment and prevention of Pneumocystis carinii pneumonitis in lower animals and humans. How effective the drug combination is in eradicating P. carinii from the host is not known. The immunosuppressed rat model was used to determine whether or not trimethoprim-sulfamethoxazole effectively eradicated the organism. Animals treated w...

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ژورنال

عنوان ژورنال: Journal of the American Academy of Dermatology

سال: 2019

ISSN: 0190-9622

DOI: 10.1016/j.jaad.2019.04.039